Besides the facilitation of cell regeneration and DNA synthesis, vitamin B12 (also known as cobalamin) plays an important role in the proper functioning of the human central nervous system and brain. With the help of its biologically active fragment (holotranscobalamin, holoTC), the body’s vitamin B12 supply can be determined more accurately than with the serum total vitamin B12 level, as it shows the early deficiency state.
Vitamin B12 deficiency is the most common among vegans, pregnant women, and elder people. In their case, early detection of vitamin B12 deficiency can contribute to the prevention and slowdown of irreversible neurological damage, cognitive impairment, and the development of dementia. Cognitive disorders (memory loss, language, and mental disorders) are a major risk factor for Alzheimer’s disease, and like this, the body’s vitamin B12 levels also indirectly affect its progress.