Uric acid is the end product of purine compounds, which make up nucleic acids (DNA, RNA). It enters the bloodstream when the absorbed nutrients or cells in the body are broken down. More than three-quarters are excreted in the urine through the kidneys, while the remainder is excreted in the faeces. If uric acid is overproduced or not excreted in sufficient quantities, the excess accumulates and crystallizes in the synovial fluid causing gout but can also cause kidney stones when deposited in the kidneys.
What does the test show?
The test shows the concentration of uric acid in the blood. The uric acid content of a healthy body is around 1g.
In which cases is it recommended to perform the test?
In case of joint pain or inflammation, a specialist may order an examination to rule out or confirm the suspicion of gout, but if renal function is impaired, it may also be necessary to measure uric acid levels. In addition, uric acid levels are usually monitored during radiotherapy and chemotherapy to determine if these treatments have caused cell death, as uric acid levels increase in this case.
What sample is needed for the test?
A blood sample taken from a vein is needed for the test.
What can the result indicate?
Uric acid level can be affected by several factors (gender, age, eating habits). It can be high if too much is produced or not excreted in the required amount, but protein-rich foods (e.g., offal), excessive alcohol consumption, and certain medications also increase its level. Uric acid levels may also be elevated in diabetic and renal patients, as well as in patients receiving chemotherapy and radiation therapy.
Elevated uric acid levels can cause gout.
What to do after the test?
The test alone cannot diagnose any diseases, and in all cases consult an internist or haematologist to determine the exact diagnosis and necessary therapy.