The so-called CH50 laboratory test is nothing but total complement activity. Its main task is to destroy pathogens. Complement is a non-antigen-specific executive system of innate immunity. The complement system consists of nearly 30 proteins, proteases, receptor proteins, and proteins with special functions.
The test measures the level of complement proteins. It can be used to determine the role of complement proteins in the development of a given infection or in the occurrence of an autoimmune process. The test can detect the possible absence or malfunction of complement proteins.