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CH 50 complement activity test

CH50 is a functional test of complement activity. It shows the function of all complement factors C1 to C9 and the complement system formed by the substances that regulate them.

What is CH50 and what is its function?

The so-called CH50 laboratory test is nothing but total complement activity. Its main task is to destroy pathogens. Complement is a non-antigen-specific executive system of innate immunity. The complement system consists of nearly 30 proteins, proteases, receptor proteins, and proteins with special functions.

What does the test measure?

The test measures the level of complement proteins. It can be used to determine the role of complement proteins in the development of a given infection or in the occurrence of an autoimmune process. The test can detect the possible absence or malfunction of complement proteins.

When is the test recommended?

  • In case of inflammation of unknown origin
  • In case of recurrent bacterial infection
  • In case of symptoms suggestive of autoimmune disease.

What are autoimmune diseases?

In case of autoimmune diseases, the body’s immune system does not recognize its own cells, identifies them as foreign, and then attacks them. We distinguish between an autoimmune disease that affects a specific organ and an autoimmune disease that affects the entire organ system.

How do I prepare for the test?

Having an empty stomach is not required for the test.

When is the result expected?

After the 21st working day following the test.

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