Causes of hair loss laboratory test
We examine the hormonal abnormalities, immune diseases, deficiency conditions, hematopoietic abnormalities, inflammations, and liver function abnormalities underlying abnormal patchy or diffuse hair loss. We recommend our tests for both men and women.
What may be behind hair loss?
Hair loss is greatly influenced by hereditary factors, hair loss may occur in postmenopausal women, but more serious diseases, such as thyroid and gynaecological problems, can also cause the complaint. Occasionally, hair loss can occur as a side effect of a medicine, in the form of inflammatory processes in the body (inflammation of the teeth or gums), a fungal infection of the scalp, or a lack of vitamins and minerals.
In women, hormonal changes and stress can also increase the amount of hair loss.
Items tested in the cause of hair loss laboratory package
Blood counts include white and red blood cell, haemoglobin and haematocrit, platelet counts, and red blood cell and white blood cell parameters. White blood cells are found throughout the body, both in the blood and in the lymphatic system. The hormone that stimulates the production of red blood cells is the erythropoietin, which is produced by the kidneys. Red blood cells carry oxygen in our bodies and also play a role in transporting carbon dioxide.
It draws attention to the existence of an abnormal process in the body, it is suitable for monitoring diseases. Its value is increased in case of infectious diseases, inflammation and malignancies, severe anaemia, kidney and thyroid disease.
C-reactive protein. It is a sensitive indicator of inflammation, the level of which increases in proportion to the severity of the condition. Once the inflammation has passed, its value decreases rapidly. In the case of more severe inflammation, its value can be high (up to several hundred).
RF (Rheumatic Factor)
One of the most common systemic autoimmune diseases of our time is rheumatoid arthritis (RA). RF is typically an IgM or IgG class immunoglobulin that forms an immune complex in the circulation or synovial fluid with other immunoglobulins. Symptoms of the disease include prolonged morning stiffness of the joints, swelling, the appearance of lumps under the skin, joint deposits that can be detected by X-ray, and changes in the cartilage and bones as the disease progresses.
Examination of liver function
The liver is the largest gland in the human body responsible for detoxification. Its role is essential for the normal functioning of metabolic processes.
Items tested in the liver function laboratory package: bilirubin, GOT, GPT, GGT, AP, albumin, cholinesterase.
Examination of thyroid function
In connection with the examination of hair loss, the values of TSH, T4, anti-TPO, anti-TG are examined among the thyroid functions.
Zinc is present in all cells of our body, but its distribution is not even. Its concentration in the brain, heart, lungs, and muscles is quite constant, while the amount of zinc in the blood, bone, and hair is also affected by food. Most of it – ninety percent – is found in the musculoskeletal system.
Iron is an important component of the oxygen-carrying protein in the blood, haemoglobin. In the case of iron deficiency, anaemia develops, the oxygen-carrying capacity of the blood decreases, and the symptoms are fatigue, dizziness, and weakness. In the case of iron deficiency, it must be ascertained whether it is due to increased loss (bleeding) or chronic illness (inflammation, cancer).
Transferrin is the major iron-carrying protein in the blood. From the degree of iron saturation, it can be inferred that the body’s iron stores are full. Transferrin concentrations are reduced in malnutrition and other conditions that cause a decrease in plasma proteins.
In case of malabsorption, malnutrition, weakness and continued unhealthy lifestyle, it is recommended to request its examination. The human body is not able to synthesize, it absorbs the required amount through food. Vitamin B12 is essential for tissue and cell regeneration and DNA synthesis. Folic acid and vitamin B12, in addition to the proper functioning of the nervous system, are essential for cell division. This is why they are extremely important in foetal development.
Celiac specific antibodies
The test aims to detect autoantibodies that the immune system produces in response to dietary proteins (gluten and gliadin) in wheat, barley and rye. The produced autoantibodies cause inflammation in the intestines and damage the intestinal walls. This in turn causes symptoms associated with malnutrition and malabsorption.
Electrophoresis is used to detect the presence of abnormal proteins or the absence of certain protein components. The method can be used to identify different groups of proteins. The body tries to maintain a constant amount of protein even by compensating for the lack of one protein fraction with the overproduction of the other. Because blood protein levels are quite constant, electrophoretic testing of proteins excreted in the urine often provides useful information about the disease.
Testosterone is not only produced in the male testicles, but occurs in the adrenal glands of both men and women. In women, albeit in small amounts, in the ovaries as well. In women, testosterone is converted to oestradiol, the main female sex hormone. Testosterone testing is used to diagnose various conditions: infertility, excessive hair growth, or masculine traits.
SHBG (Sex Hormone Binding Globulin)
SHBG is typically found to be particularly elevated in women at higher concentrations than in men, during advanced pregnancy, and when taking oestrogen. Testosterone is mainly bound to SHBG in the circulation, its concentration may be affected by the amount of transport protein. SHBG levels are usually measured in addition to total testosterone as an additional test.
ANA and ENA (antinuclear antibody)
The test shows the presence of antinuclear antibody in the bloodstream. Antibodies are produced by the immune system against foreign substances (viruses, bacteria) that enter the body. Sometimes, the immune system produces substances that attack the body’s own cells and tissues instead of foreign substances, called autoantibodies. It is associated with several autoimmune diseases, but most commonly appears in systemic lupus erythematosus.
The result of a laboratory test for hair loss alone is not enough to make a diagnosis. If your complaints persist, our experienced internal medicine specialists are at your disposal.
How do I prepare for the test?
Having an empty stomach is required for the laboratory examination of the cause of hair loss.
When is the result expected?
After the 7th working day after the test.